The technology used in Moderna’s COVID-19 vaccine carries toxicity risks, scientists with the company said in a new paper.
“A major challenge now is how to efficiently de-risk potential toxicities associated with mRNA technology,” the scientists wrote in the paper, which was published by Nature Reviews Drug Discovery on Jan. 23.
The Moderna and Pfizer COVID-19 vaccines use modified messenger ribonucleic acid (mRNA) technology. The mRNA is delivered by lipid nanoparticles (LNP).
The toxicity risks include “lipid nanoparticle structural components, production methods, route of administration and proteins produced from complexed mRNAs,” the authors of the paper wrote.
Authors of the paper include Moderna employees Eric Jacquinet and Dimitrios Bitounis and Maximillian Rogers, who was working at Moderna when the paper was being done.
Moderna didn’t respond to a request for comment.
The mRNA vaccines have multiple known side effects, including heart inflammation and severe allergic shock. Those may stem from hypersensitivity reactions, which can be elicited by “any LNP-mRNA component” but are most likely triggered by PEGlyated lipid nanoparticles, which is “the most potentially reactogenic component,” according to the scientists.
Polyethylene glycol, or PEG, an ingredient in the Pfizer and Moderna COVID-19 vaccines, is known to cause allergic reactions. Outside scientists are divided over the mechanism behind the heart inflammation, while Pfizer has posited that the LNPs are behind the issue.
The new paper drew from prior publications and other data. The authors didn’t carry out any new experiments.
Some of the papers cited included those that have found mRNA and the spike protein delivered by Moderna’s vaccine in various parts of human beings weeks or months after vaccination, despite health officials claiming when the vaccines were rolled out that such materials would exit the body within days.
The scientists said that Moderna’s COVID-19 vaccine is “safe and effective” and hailed the development of an updated vaccine as “[demonstrating] the rapid timeline for modifications with mRNA technology in the clinic.” Due to the “transient nature of mRNA,” however, “repeat administration may be necessary,” they said.
The scientists later noted that reducing risks of toxicities with mRNA-based vaccines and drugs is necessary but “complicated.” That can be accomplished through a multipronged approach that includes advanced testing in laboratories and adjusts preclinical, animal trials to better account for “differences in human and animal physiology.”
Moderna and other companies are currently testing a number of new mRNA products, including influenza vaccines and cancer treatments.
“Thanks to the mRNA platform we built, we have an exciting pipeline, with up to 15 launches in the next five years,” Stephane Bancel, Moderna’s CEO, told investors in the company’s most recent earnings call.
The paper’s corresponding author, Mansoor Amiji of Northeastern University’s Departments of Pharmaceutical Sciences and Chemical Engineering, referred a request for comment to Mr. Bitounis, who didn’t provide any answers.
Dr. Malone Reacts
Dr. Robert Malone, who helped invent the mRNA technology, said the paper downplayed the range of risks that have been linked to the mRNA-based vaccines and may be part of a limited hangout, or a propaganda technique.
That technique, a form of misdirection, involves people offering some information to obscure or prevent the discovery of other information.
“My most generous interpretation of the overall intent of the article is that this article summarizes and represents information concerning risks and toxicities of this platform technology which Moderna wishes to have disclosed in a manner which puts the firm, its activities and the underlying platform technology in the best possible light,” Dr. Malone, who wasn’t involved with the paper, wrote in his review.
“A less generous interpretation of intent is that this article represents a subtle form of propaganda strategy commonly referred to as a limited hangout.”
New report denounces Havana and claims ‘campaign of subversion’ has infiltrated highest levels of US government
"...There is overwhelming evidence that the machinery of the Cuban Government has been progressively organized around… a fundamental hatred of the United States,” the report stated. “Many of the most significant upheavals in recent American political history —from the George Floyd riots to the rise of Antifa to the explosion of pro-terrorist activism on American college campuses— can be linked, in some way, shape, or form to Cuban influence.”
The report doesn’t just hand-wave. It names names. It details how the Venceremos Brigade and other “revolutionary tourism” programs have funneled thousands of American activists to Havana for ideological (and sometimes literal) weapons training.
The Venceremos Brigade has brought 10,000 American activists to Cuba since 1969. This is because nothing says “I am fighting for the oppressed working class” quite ...
Now there is a plan! Of course dumb Canadians will not have the courage to vote with their brains, instead of their propagandized feelings of fear.
Canada’s economy is stalling badly.
We just endured the worst decade for real GDP growth per person since the Great Depression.
Over the past ten years, real GDP per capita limped along at an average of just 0.6% annually.
And Bloomberg’s consensus forecast for 2026? A paltry 0.7%.
Why does GDP matter?
Because family disposable income follows GDP like a shadow. Anemic economic growth resulting from lower investment means stagnant wages. Period.
The Liberals and fake Conservatives won't fix this.
The People's Party has a comprehensive plan to unleash private investment, supercharge productivity, and put more money back into your pocket:
Make the Accelerated Capital Cost Allowance (ACCA) permanent – Let businesses write off capital investments rapidly and skyrocket cash flow.
End Corporate Welfare – Zero subsidies. Zero bailouts. Zero regional ...
