The Lions
Politics • Culture • Education
A group of friends with mostly centrist or conservative viewpoints who share resources and ideas about the governance of Alberta and Canada and about world events and trends.
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November 14, 2024

They're trialing self-amplifying RNA-LNP-based products for H5N1 in humans

"...GMO products need GMO licensing - a cautionary tale
So. Many. Questions. For example, beyond the use of the word pandemic in the study title, why is this product being called a vaccine? Why is a new version of a product riddled with unresolved compendial standard issues being trialed?

ARCT-2304 is a gene-therapy-based prodrug that uses self-amplifying RNA technology (specifically, the RNA-dependent RNA polymerase (RdRP) gene, which allows it to replicate autonomously) that originates from an Alphavirus. Just so you know, this makes these products genetically-modified organisms (GMOs) and this is because of the fact that the coding template is a modified Alphavirus genome with the virus sub-genomic bits spiked out and the spike gene ‘spiked in’. The genetic material is capable of reproduction...
https://jessicar.substack.com/p/theyre-trialing-self-amplifying-rna

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