Landmark Cleveland Clinic Study Finds Flu Vaccine Ineffective—And Possibly Harmful—for Working Adults in 2024-2025
Vaccinated at Higher Risk of Flu
Of the 53,402 employees analyzed, 82.1% received the flu vaccine. Yet, the cumulative incidence of influenza climbed faster in the vaccinated than the unvaccinated cohort. A total of 1,079 infections occurred—overwhelmingly, influenza A. After multivariable adjustment, the vaccinated had a 27% higher risk of influenza infection (HR 1.27, 95% CI: 1.07–1.51, P = 0.007), translating to a vaccine effectiveness of –26.9%. These results are not due to testing bias: while vaccinated individuals were more likely to get tested, their test positivity rate was nearly identical to the unvaccinated, indicating a true excess of infections.
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https://x.com/bcbluecon/status/1961166703280492674
